Publications

Lutterotti, A., Sospedra, M., Martin, R. Antigen-specific therapies in MS – current concepts and novel approaches. J. Neurol. Sci. 274: 18-22 (2008) (doi: 10.1016/j.jns.2008.05.021.)

Lutterotti, A., Yousef, S., Sputtek, A., Stürner, K., Stellmann, J.-P., Breiden, P., Reinhardt, S., Schulze, C., Bester, M., Heesen, C., Schippling, S., Miller, S.D., Sospedra, M., Martin, R. Induction of tolerance by autologous peptide-coupled cells in multiple sclerosis. Sci. Transl. Med., 5: 188ra75. (2013)(doi: 10.1126/scitranslmed.3006168.)

Lutterotti, A., Martin, R. Antigen-specific tolerization approaches in multiple sclerosis. Expert Opin. Investig. Drugs, 23 (1):9-20 (2014)(doi: 10.1517/13543784.2014.844788.)

Jelcic, Iv.*, Al Nimer, F.*, Wang, J., Lentsch, V., Planas, R., Jelcic, Il., Madjowski, A., Ruhrmann, S., Faigle, W., Frauenknecht, K., Pinilla, C., Santos, R., Hammer, C., Ortiz, Y., Opitz, L., Grönlund, H., Rogler, G., Boyman, O., Reynolds, R., Lutterotti, A., Olsson, T., Piehl, F., Sospedra, M., Martin, R. Memory B cells activate brain-homing, autoreactive CD4+T cells in multiple sclerosis. Cell, 175: 1–16; September 20, 2018; epub ahead of print on August 31, 2018 (2018)(doi: 10.1016/j.cell.2018.08.011.)

Planas, R., Santos, R., Tomas-Ojer, P., Cruciani, C., Lutterotti, A., Faigle, W., Schaeren-Wiemers, N., Espejo, C., Eixarch, H., Pinilla, C., Martin, R., Sospedra, M. GDP-L-fucose synthase as a novel CD4+ T cell-specific autoantigen in DRB3*02:02 multiple sclerosis patients. Sci. Transl. Med. 2018 Oct 10;10(462). pii: eaat4301 (2018)(doi: 10.1126/scitranslmed.aat4301.)

Wang, J., Jelcic, Iv., Mühlenbruch, L., Haunerdinger, V., Toussaint, N.C., Zhao, Y., Cruciani, C., Faigle, W., Naghavian, R., Foege, M., Binder, T.M.C., Eierman, T., Opitz, L., Fuentes-Font, L., Reynolds, R., Kwok, W.W., Nguyen, J., Lee, J.-H., Lutterotti, A., Münz, C., Rammensee, H.G., Hauri-Hohl, M., Sospedra, M., Stevanovic, S., Martin. R. Tightly linked HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis. Cell, 183(5):1264-1281; November 25, 2020 a 2020; epub ahead of print on Oct. 2; (2020)(doi: 10.1016/j.cell.2020.09.054. Epub 2020 Oct 21.)

Lutterotti, A., Hayward-Könnecke, H., Sospedra, M., Martin, R. Antigen-specific immune tolerance in multiple sclerosis - promising approaches and how to bring them to patients. Front. Immunol., 2021 Mar 22;12:640935 (2021)(doi: 10.3389/fimmu.2021.640935.)

Cruciani, C., Puthenparampil, M., Tomas-Ojer, P., Jelcic, Iv., Docampo M.J., Planas, R., Manogaran, P., Opfer, R., Wicki, C.A., Reindl, M., Jelcic, Il., Lutterotti, A., Martin, R., Sospedra, M. T cell specificity influences disease heterogeneity in multiple sclerosis. Neurology Neuroimmunol. Neuroinflamm., 2021;8:e1075 (2021) (doi:10.1212/NXI.0000000000001075.)

Docampo, M.J., Lutterotti, A., Sospedra, M., Martin, R. Mechanistic and biomarker studies to demonstrate immune tolerance in multiple sclerosis. Front. Immunol., 2022 Jan 5;12:787498. doi: 10.3389/fimmu.2021.787498. eCollection 2021 (2022)(doi: 10.3389/fimmu.2021.787498.)